Pro-cathepsin H · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P09668. Use UniProt P09668 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P09668 as the stable identity anchor, then attach disease evidence before program review.
Pro-cathepsin H
Review this target as Pro-cathepsin H, mapped to UniProt P09668. Sequence length is 335 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Pro-cathepsin H as ChEMBL target CHEMBL2225, mapped to UniProt P09668. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Pro-cathepsin H |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P09668 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Pro-cathepsin H |
| UniProt Accession | P09668 |
| Component Type | Protein |
| Sequence Length | 335 aa |
Pro-cathepsin H
Review this target as Pro-cathepsin H, mapped to UniProt P09668. Sequence length is 335 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL371420 | 9.34 | Ki | 0.46 | Preclinical |
| CHEMBL190121 | 8.85 | Ki | 1.4 | Preclinical |
| CHEMBL113948 | 7.75 | IC50 | 18.0 | Preclinical |
| CHEMBL114161 | 7.4 | IC50 | 40.0 | Preclinical |
| CHEMBL183812 | 7.4 | IC50 | 40.0 | Preclinical |
| CHEMBL5848986 | 6.96 | IC50 | 110.0 | Preclinical |
| CHEMBL567341 | 6.9 | IC50 | 125.89 | Preclinical |
| CHEMBL514348 | 6.86 | Ki | 137.0 | Preclinical |
| CHEMBL492175 | 6.84 | IC50 | 145.0 | Preclinical |
| CHEMBL203663 | 6.72 | IC50 | 190.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 40 | 34 | 6.2 |
| assay format | 11 | 13 | 4.7 |