Compound Detail
CHEMBL5848986
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Basic Information
| ChEMBL ID | CHEMBL5848986 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DRRLOKQBVIVNIT-AWEZNQCLSA-N |
7
Targets
22
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
404.4
MW (Da)
2.99
ALogP
4
HBA
2
HBD
81.4
PSA (Ų)
0.36
QED
0
Ro5 Violations
10
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 22 meas. best 7.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cathepsin K CHEMBL268 | IC50 | 7.7 | 7.7 | 20.0 | 4 |
| Pro-cathepsin H CHEMBL2225 | IC50 | 6.96 | 6.96 | 110.0 | 4 |
| Cathepsin B CHEMBL4072 | IC50 | 6.31 | 6.31 | 485.0 | 4 |
| Cathepsin F CHEMBL2517 | IC50 | 6.3 | 6.3 | 500.0 | 2 |
| Procathepsin L CHEMBL3837 | IC50 | 6.16 | 6.16 | 700.0 | 4 |
| Cathepsin L2 CHEMBL3272 | IC50 | 5.24 | 5.24 | 5720.0 | 2 |
| Cathepsin S CHEMBL2954 | IC50 | 5.0 | 5.0 | 9980.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine