Assay Detail
Binding
CHEMBL830350
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Binding affinity for protein kinase C-alpha C1a and C1b domains
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Conformationally constrained analogues of diacylglycerol (DAG). 23. Hydrophobic ligand-protein interactions versus ligand-lipid interactions of DAG-lactones with protein kinase C (PK-C).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.27 | 8.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL96766 | — | — | 1 | 8.54 |
| CHEMBL137386 | — | — | 1 | 8.49 |
| CHEMBL137701 | — | — | 1 | 8.08 |
| CHEMBL136760 | — | — | 1 | 7.95 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL96766 | — | Ki | = | 2.9 | nM | 8.54 |
| CHEMBL137386 | — | Ki | = | 3.25 | nM | 8.49 |
| CHEMBL137701 | — | Ki | = | 8.32 | nM | 8.08 |
| CHEMBL136760 | — | Ki | = | 11.25 | nM | 7.95 |