Assay Detail
Binding
CHEMBL830368
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Inhibition constant against human cathepsin L using Cbz-Phe-Arg-AMC
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Acyclic cyanamide-based inhibitors of cathepsin K.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.45 | 10.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL191558 | — | — | 1 | 10.44 |
| CHEMBL371420 | — | — | 1 | 9.10 |
| CHEMBL189149 | — | — | 1 | 5.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL191558 | — | Ki | = | 0.036 | nM | 10.44 |
| CHEMBL371420 | — | Ki | = | 0.79 | nM | 9.10 |
| CHEMBL189149 | — | Ki | = | 1500.0 | nM | 5.82 |