Assay Detail
Binding
CHEMBL831670
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Inhibitory concentration against human alpha-galactosidase
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Biological properties of D- and L-1-deoxyazasugars.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.76 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL110458 | MIGALASTAT | 4.0 | 1 | 7.16 |
| CHEMBL176021 | — | — | 1 | 4.35 |
| CHEMBL368121 | — | — | 1 | - |
| CHEMBL369046 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL110458 | MIGALASTAT | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL176021 | — | IC50 | = | 45000.0 | nM | 4.35 |
| CHEMBL368121 | — | IC50 | = | 390000.0 | nM | - |
| CHEMBL369046 | — | IC50 | = | 920000.0 | nM | - |