Assay Detail
Binding
CHEMBL831814
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration required towards 5-hydroxytryptamine 4 receptor in guinea pig striatum using [3H]GR-113808 as the radioligand
4
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Striatum |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Azaadamantane benzamide 5-HT4 agonists: gastrointestinal prokinetic SC-54750.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 6.56 | 7.13 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3085015 | — | — | 2 | 7.13 |
| CHEMBL295155 | — | — | 2 | 6.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3085015 | — | EC50 | = | 73.6 | nM | 7.13 |
| CHEMBL295155 | — | EC50 | = | 262.0 | nM | 6.58 |
| CHEMBL295155 | — | EC50 | = | 538.0 | nM | 6.27 |
| CHEMBL3085015 | — | EC50 | = | 545.0 | nM | 6.26 |