Assay Detail
Binding
CHEMBL831915
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Inhibitory activity against rat liver Histone deacetylase with substrate 3a
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Subtype selective substrates for histone deacetylases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.85 | 7.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1790587 | — | — | 1 | 7.25 |
| CHEMBL140000 | — | — | 1 | 7.11 |
| CHEMBL360194 | — | — | 1 | 6.86 |
| CHEMBL143047 | — | — | 1 | 6.59 |
| CHEMBL99392 | — | — | 1 | 6.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1790587 | — | IC50 | = | 55.7 | nM | 7.25 |
| CHEMBL140000 | — | IC50 | = | 78.2 | nM | 7.11 |
| CHEMBL360194 | — | IC50 | = | 137.0 | nM | 6.86 |
| CHEMBL143047 | — | IC50 | = | 256.0 | nM | 6.59 |
| CHEMBL99392 | — | IC50 | = | 349.0 | nM | 6.46 |