Assay Detail
Functional
CHEMBL832196
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Inhibitory concentration against dipeptidyl peptidase IV of porcine kidney
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Sus scrofa |
| Tissue | Kidney |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and DP-IV inhibition of cyano-pyrazoline derivatives as potent anti-diabetic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.11 | 6.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL184572 | — | — | 1 | 6.89 |
| CHEMBL363542 | — | — | 1 | 6.36 |
| CHEMBL184651 | — | — | 1 | 6.02 |
| CHEMBL185222 | — | — | 1 | 5.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL184572 | — | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL363542 | — | IC50 | = | 440.0 | nM | 6.36 |
| CHEMBL184651 | — | IC50 | = | 960.0 | nM | 6.02 |
| CHEMBL185222 | — | IC50 | = | 6820.0 | nM | 5.17 |