Assay Detail
Functional
CHEMBL832479
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Effective concentration resulting in a 50% reduction in virus production in BHK cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Sindbis virus |
| Cell Type | BHK |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis, and evaluation of dioxane-based antiviral agents targeted against the Sindbis virus capsid protein.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 5.20 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL364472 | — | — | 1 | 6.00 |
| CHEMBL190235 | — | — | 1 | 4.40 |
| CHEMBL192713 | — | — | 1 | - |
| CHEMBL193302 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL364472 | — | EC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL190235 | — | EC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL192713 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL193302 | — | EC50 | > | 100000.0 | nM | - |