Assay Detail
Binding
CHEMBL832651
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Inhibitory concentration against Escherichia coli Ile-tRNA synthetase
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Deoxyribosyl analogues of methionyl and isoleucyl sulfamate adenylates as inhibitors of methionyl-tRNA and isoleucyl-tRNA synthetases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.41 | 6.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1163069 | — | — | 1 | 6.58 |
| CHEMBL1161708 | — | — | 1 | 5.19 |
| CHEMBL1789970 | — | — | 1 | 4.46 |
| CHEMBL1789972 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1163069 | — | IC50 | = | 265.0 | nM | 6.58 |
| CHEMBL1161708 | — | IC50 | = | 6400.0 | nM | 5.19 |
| CHEMBL1789970 | — | IC50 | = | 35000.0 | nM | 4.46 |
| CHEMBL1789972 | — | IC50 | = | 280000.0 | nM | - |