Assay Detail
Binding
CHEMBL832785
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Inhibitory activity against beta-Glucosidase from sweet almond
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Prunus dulcis |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Alpha-1-C-alkyl-1-deoxynojirimycin derivatives as potent and selective inhibitors of intestinal isomaltase: remarkable effect of the alkyl chain length on glycosidase inhibitory profile.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.65 | 4.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL364554 | — | — | 1 | 4.92 |
| CHEMBL186291 | — | — | 1 | 4.57 |
| CHEMBL186068 | — | — | 1 | 4.47 |
| CHEMBL184028 | — | — | 1 | - |
| CHEMBL362754 | — | — | 1 | - |
| CHEMBL186150 | — | — | 1 | - |
| CHEMBL187158 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL364554 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL186291 | — | IC50 | = | 27000.0 | nM | 4.57 |
| CHEMBL186068 | — | IC50 | = | 34000.0 | nM | 4.47 |
| CHEMBL184028 | — | IC50 | = | 150000.0 | nM | - |
| CHEMBL362754 | — | IC50 | = | 900000.0 | nM | - |
| CHEMBL186150 | — | IC50 | = | 350000.0 | nM | - |
| CHEMBL187158 | — | IC50 | = | 150000.0 | nM | - |