Assay Detail
Binding
CHEMBL832826
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Binding affinity for recombinant human glucocorticoid receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Design and evaluation of novel nonsteroidal dissociating glucocorticoid receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.92 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL433586 | — | — | 1 | 8.30 |
| CHEMBL426262 | — | — | 1 | 6.78 |
| CHEMBL186893 | — | — | 1 | 5.68 |
| CHEMBL182853 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL433586 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL426262 | — | IC50 | = | 165.0 | nM | 6.78 |
| CHEMBL186893 | — | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL182853 | — | IC50 | > | 2000.0 | nM | - |