Assay Detail
Binding
CHEMBL833026
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human androgen receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Antidiabetic activity of passive nonsteroidal glucocorticoid receptor modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.88 | 8.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1276308 | MIFEPRISTONE | 4.0 | 1 | 8.06 |
| CHEMBL185265 | — | — | 1 | 5.80 |
| CHEMBL190109 | — | — | 1 | 5.44 |
| CHEMBL363151 | — | — | 1 | 5.19 |
| CHEMBL190225 | — | — | 1 | 4.93 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1276308 | MIFEPRISTONE | IC50 | = | 8.8 | nM | 8.06 |
| CHEMBL185265 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL190109 | — | IC50 | = | 3600.0 | nM | 5.44 |
| CHEMBL363151 | — | IC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL190225 | — | IC50 | = | 11700.0 | nM | 4.93 |