Assay Detail
Functional
CHEMBL833088
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Inhibitory concentration against DNA synthesis in LNZ308 glioblastoma cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Glioblastoma |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Endothelin-converting enzyme-1 inhibition and growth of human glioblastoma cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.56 | 4.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL191879 | — | — | 1 | 4.80 |
| CHEMBL425383 | — | — | 1 | 4.62 |
| CHEMBL367315 | — | — | 1 | 4.40 |
| CHEMBL194651 | — | — | 1 | 4.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL191879 | — | IC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL425383 | — | IC50 | = | 24000.0 | nM | 4.62 |
| CHEMBL367315 | — | IC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL194651 | — | IC50 | = | 40000.0 | nM | 4.40 |