Assay Detail
Functional
CHEMBL833169
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inhibition concentration required against human enterovirus 71 (2086) genotype C was determined by plaque reduction assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Enterovirus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and antienteroviral activity of a series of novel, oxime ether-containing pyridyl imidazolidinones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.78 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL365461 | — | — | 1 | 8.40 |
| CHEMBL45426 | — | — | 1 | 7.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL365461 | — | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL45426 | — | IC50 | = | 70.0 | nM | 7.16 |