Assay Detail
Functional
CHEMBL833238
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration required to inhibit varicella zoster virus replication in HFF cells in cytopathic reduction assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human alphaherpesvirus 3 |
| Cell Type | HFF |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Nucleotides and pronucleotides of 2,2-bis(hydroxymethyl)methylenecyclopropane analogues of purine nucleosides: synthesis and antiviral activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 5.20 | 5.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL195174 | — | — | 1 | 5.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL195174 | — | EC50 | = | 6300.0 | nM | 5.20 |