Assay Detail

CHEMBL833827

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Functional

Effective concentration to inhibit the replication of HIV-1 R5 strain

ChEMBL ↗

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Target

Human immunodeficiency virus 1 (CHEMBL378) ↗

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Primary target Human immunodeficiency virus 1

CHEMBL378

Anchored from Assay target.

Protein identity Human immunodeficiency virus 1

Disease frame Disease evidence pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Human immunodeficiency virus 1
Confidence	1 — Organism
Curated By	Intermediate

Target

Human immunodeficiency virus 1 (CHEMBL378) ↗

Type	ORGANISM
Organism	Human immunodeficiency virus 1

Publication

New approaches toward anti-HIV chemotherapy.

De Clercq E.
J Med Chem (2005) 48 : 1297 -1313
PubMed 15743172 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	8.96	8.96

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL207004	—	—	1	8.96

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL207004	—	EC50	=	1.1	nM	8.96