Assay Detail
Functional
CHEMBL833840
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Concentration required to protect CEM cells against Mutant L100I Strain
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CCRF-CEM |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.61 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL393003 | — | — | 1 | 5.70 |
| CHEMBL53554 | THIAZOLOBENZIMIDAZOLE | — | 1 | 5.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL393003 | — | EC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL53554 | THIAZOLOBENZIMIDAZOLE | EC50 | = | 3120.0 | nM | 5.51 |