Assay Detail
Functional
CHEMBL833857
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Inhibitory concentration required to produce cytotoxicity against HEK293 cells
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Solid-phase synthesis and anti-infective activity of a combinatorial library based on the natural product anisomycin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.31 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL423192 | ANISOMYCIN | — | 1 | 7.70 |
| CHEMBL364633 | — | — | 1 | 5.70 |
| CHEMBL189180 | — | — | 1 | 5.10 |
| CHEMBL361092 | — | — | 1 | 5.10 |
| CHEMBL188110 | — | — | 1 | 5.05 |
| CHEMBL364428 | — | — | 1 | 5.00 |
| CHEMBL186210 | — | — | 1 | 5.00 |
| CHEMBL425175 | — | — | 1 | 4.96 |
| CHEMBL413961 | — | — | 1 | 4.80 |
| CHEMBL364389 | — | — | 1 | 4.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL423192 | ANISOMYCIN | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL364633 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL189180 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL361092 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL188110 | — | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL364428 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL186210 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL425175 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL413961 | — | IC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL364389 | — | IC50 | = | 22000.0 | nM | 4.66 |