Assay Detail
Functional
CHEMBL833925
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Inhibition of ADP-induced aggregation of human platelets
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Metabolism investigation leading to novel drug design: orally active prostacyclin mimetics. Part 4.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 7.49 | 8.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2373410 | — | — | 1 | 8.24 |
| CHEMBL189943 | — | — | 1 | 7.92 |
| CHEMBL362960 | — | — | 1 | 7.85 |
| CHEMBL363350 | — | — | 1 | 7.25 |
| CHEMBL132589 | — | — | 1 | 7.22 |
| CHEMBL363405 | — | — | 1 | 7.01 |
| CHEMBL365743 | — | — | 1 | 6.94 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2373410 | — | IC50 | = | 5.8 | nM | 8.24 |
| CHEMBL189943 | — | IC50 | = | 12.0 | nM | 7.92 |
| CHEMBL362960 | — | IC50 | = | 14.0 | nM | 7.85 |
| CHEMBL363350 | — | IC50 | = | 56.0 | nM | 7.25 |
| CHEMBL132589 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL363405 | — | IC50 | = | 98.0 | nM | 7.01 |
| CHEMBL365743 | — | IC50 | = | 116.0 | nM | 6.94 |