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Assay Detail

CHEMBL833939

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In vitro effective concentration against HIV-1 in MT-4 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MT4
Confidence 1 — Organism
Curated By Intermediate

Target

MT4 (CHEMBL388)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis, antiviral activity, and mechanism of drug resistance of D- and L-2',3'-didehydro-2',3'-dideoxy-2'-fluorocarbocyclic nucleosides.
Wang J, Jin Y, Rapp KL, Bennett M, Schinazi RF, Chu CK.
J Med Chem (2005) 48 : 3736 -3748
PubMed 15916425 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.34 5.34

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL372283 CARBOVIR 1 5.34

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL372283 CARBOVIR IC50 = 4600.0 nM 5.34