Assay Detail
Functional
CHEMBL833965
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Inhibitory concentration against DNA synthesis in LN18 glioblastoma cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Glioblastoma |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Endothelin-converting enzyme-1 inhibition and growth of human glioblastoma cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.75 | 4.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL177000 | — | — | 1 | 4.92 |
| CHEMBL193490 | — | — | 1 | 4.75 |
| CHEMBL192441 | — | — | 1 | 4.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL177000 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL193490 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL192441 | — | IC50 | = | 27000.0 | nM | 4.57 |