Assay Detail
Functional
CHEMBL834049
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Effective concentration to inhibit 50% of hepatitis C virus replication in a cell culture model
43
Total Activities
43
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepacivirus hominis |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and antiviral activity of helioxanthin analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 43 | 5.24 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL367646 | — | — | 1 | 6.00 |
| CHEMBL175656 | — | — | 1 | 5.52 |
| CHEMBL175937 | — | — | 1 | 5.52 |
| CHEMBL179030 | — | — | 1 | 5.52 |
| CHEMBL180214 | — | — | 1 | 5.52 |
| CHEMBL175499 | — | — | 1 | 5.52 |
| CHEMBL425330 | — | — | 1 | 5.00 |
| CHEMBL605342 | — | — | 1 | 5.00 |
| CHEMBL367791 | — | — | 1 | 5.00 |
| CHEMBL175658 | — | — | 1 | 5.00 |
| CHEMBL367538 | — | — | 1 | 5.00 |
| CHEMBL366762 | — | — | 1 | 5.00 |
| CHEMBL179075 | — | — | 1 | 5.00 |
| CHEMBL368898 | — | — | 1 | 5.00 |
| CHEMBL179106 | — | — | 1 | 5.00 |
| CHEMBL361216 | — | — | 1 | - |
| CHEMBL362015 | — | — | 1 | - |
| CHEMBL176033 | — | — | 1 | - |
| CHEMBL540455 | — | — | 1 | - |
| CHEMBL175605 | — | — | 1 | - |
| CHEMBL175857 | — | — | 1 | - |
| CHEMBL359649 | — | — | 1 | - |
| CHEMBL366713 | — | — | 1 | - |
| CHEMBL175945 | — | — | 1 | - |
| CHEMBL368536 | — | — | 1 | - |
| CHEMBL180419 | — | — | 1 | - |
| CHEMBL425145 | — | — | 1 | - |
| CHEMBL369673 | — | — | 1 | - |
| CHEMBL175899 | — | — | 1 | - |
| CHEMBL179135 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL367646 | — | EC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL175656 | — | EC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL175937 | — | EC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL179030 | — | EC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL180214 | — | EC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL175499 | — | EC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL605342 | — | EC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL367791 | — | EC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL175658 | — | EC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL425330 | — | EC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL366762 | — | EC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL179075 | — | EC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL368898 | — | EC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL367538 | — | EC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL179106 | — | EC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL361216 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL426956 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL179251 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL425698 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL175662 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL366736 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL367089 | — | EC50 | > | 3000.0 | nM | - |
| CHEMBL436474 | HELIOXANTHIN | EC50 | > | 3000.0 | nM | - |
| CHEMBL369844 | — | EC50 | > | - | nM | - |
| CHEMBL175951 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL368391 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL179253 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL368582 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL179354 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL362015 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL176033 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL540455 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL175605 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL175857 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL359649 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL366713 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL175945 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL368536 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL180419 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL425145 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL369673 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL175899 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL179135 | — | EC50 | > | 10000.0 | nM | - |