Assay Detail
Functional
CHEMBL834058
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | RH7777 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of PPARgamma, and inhibitors of autotaxin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.03 | 6.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL187459 | — | — | 1 | 6.26 |
| CHEMBL190328 | — | — | 1 | 5.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL187459 | — | EC50 | = | 546.0 | nM | 6.26 |
| CHEMBL190328 | — | EC50 | = | 1600.0 | nM | 5.80 |