Assay Detail
Functional
CHEMBL834407
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonistic effective concentration to stimulate cAMP in CHO cells stably expressing the human melanocortin-4 receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
A potent and selective nonpeptide antagonist of the melanocortin-4 receptor induces food intake in satiated mice.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 8.33 | 8.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL360716 | — | — | 1 | 8.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL360716 | — | EC50 | = | 4.7 | nM | 8.33 |