Assay Detail
Functional
CHEMBL835247
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human lymph node carcinoma of prostate (LNCaP) cell proliferation
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
11beta-alkyl-Delta9-19-nortestosterone derivatives: high-affinity ligands and potent partial agonists of the androgen receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 7.59 | 7.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL184313 | — | — | 1 | 7.77 |
| CHEMBL186467 | — | — | 1 | 7.77 |
| CHEMBL186254 | — | — | 1 | 7.77 |
| CHEMBL189306 | — | — | 1 | 7.72 |
| CHEMBL1276308 | MIFEPRISTONE | 4.0 | 1 | 7.64 |
| CHEMBL184228 | — | — | 1 | 7.26 |
| CHEMBL361245 | — | — | 1 | 7.21 |
| CHEMBL2311179 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL184313 | — | IC50 | = | 17.0 | nM | 7.77 |
| CHEMBL186467 | — | IC50 | = | 17.0 | nM | 7.77 |
| CHEMBL186254 | — | IC50 | = | 17.0 | nM | 7.77 |
| CHEMBL189306 | — | IC50 | = | 19.0 | nM | 7.72 |
| CHEMBL1276308 | MIFEPRISTONE | IC50 | = | 23.0 | nM | 7.64 |
| CHEMBL184228 | — | IC50 | = | 55.0 | nM | 7.26 |
| CHEMBL361245 | — | IC50 | = | 61.0 | nM | 7.21 |
| CHEMBL2311179 | — | IC50 | > | 100.0 | nM | - |