Assay Detail
Functional
CHEMBL836562
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Cytotoxicity against HL-60 (human fibrosarcoma) cell line at 2.5 joule/cm**2 UVA dose
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and photochemotherapeutic activity of thiopyrano[2,3-e]indol-2-ones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.68 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL196028 | — | — | 1 | 6.22 |
| CHEMBL53569 | ANGELICIN | — | 1 | 5.92 |
| CHEMBL416 | METHOXSALEN | 4.0 | 1 | 5.85 |
| CHEMBL193565 | — | — | 1 | 5.58 |
| CHEMBL197313 | — | — | 1 | 5.32 |
| CHEMBL371273 | — | — | 1 | 5.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL196028 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL53569 | ANGELICIN | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL416 | METHOXSALEN | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL193565 | — | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL197313 | — | IC50 | = | 4800.0 | nM | 5.32 |
| CHEMBL371273 | — | IC50 | = | 6200.0 | nM | 5.21 |