Assay Detail
Functional
CHEMBL837180
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Effective concentrations at which 2-fold depression of HCV RNA was observed in AVA5 cells (Huh 7 cells with subgenomic HCV replicon BB7)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepacivirus hominis |
| Cell Type | AVA5 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
5'-Homoneplanocin A inhibits hepatitis B and hepatitis C.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.14 | 5.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL310547 | — | — | 1 | 5.14 |
| CHEMBL1643 | RIBAVIRIN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL310547 | — | EC50 | = | 7300.0 | nM | 5.14 |
| CHEMBL1643 | RIBAVIRIN | EC50 | > | 100000.0 | nM | - |