Assay Detail
Functional
CHEMBL837247
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Potency by glucose stimulated insulin release from HEK 293 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
2-(4-Methoxyphenoxy)-5-nitro-N-(4-sulfamoylphenyl)benzamide activates Kir6.2/SUR1 K(ATP) channels.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.49 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL112668 | — | — | 1 | 6.10 |
| CHEMBL185449 | — | — | 1 | 5.89 |
| CHEMBL181 | DIAZOXIDE | 4.0 | 1 | 4.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL112668 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL185449 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL181 | DIAZOXIDE | IC50 | = | 33000.0 | nM | 4.48 |