Assay Detail
Functional
CHEMBL838012
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Vasodilating activity in rat aorta strip in presence of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ) at 100 uM
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Aorta |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Development of a new class of potential antiatherosclerosis agents: NO-donor antioxidants.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 4.62 | 4.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL187933 | — | — | 1 | 4.82 |
| CHEMBL188760 | — | — | 1 | 4.42 |
| CHEMBL188554 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL187933 | — | EC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL188760 | — | EC50 | = | 38000.0 | nM | 4.42 |
| CHEMBL188554 | — | EC50 | = | 4.6 | % | - |