Assay Detail
Binding
CHEMBL838564
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Inhibitory constant against hepatitis C virus NS3 protease
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Hepacivirus hominis |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Control of hepatitis C: a medicinal chemistry perspective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 11 | 6.84 | 9.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL179084 | — | — | 1 | 9.12 |
| CHEMBL349186 | — | — | 1 | 8.00 |
| CHEMBL60967 | — | — | 1 | 7.64 |
| CHEMBL417559 | — | — | 1 | 7.40 |
| CHEMBL305570 | — | — | 1 | 7.22 |
| CHEMBL62717 | — | — | 1 | 6.22 |
| CHEMBL178982 | — | — | 1 | 6.22 |
| CHEMBL82941 | — | — | 1 | 6.10 |
| CHEMBL189314 | — | — | 1 | 6.00 |
| CHEMBL24547 | — | — | 1 | 5.66 |
| CHEMBL278785 | — | — | 1 | 5.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL179084 | — | Ki | = | 0.75 | nM | 9.12 |
| CHEMBL349186 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL60967 | — | Ki | = | 23.0 | nM | 7.64 |
| CHEMBL417559 | — | Ki | = | 40.0 | nM | 7.40 |
| CHEMBL305570 | — | Ki | = | 60.0 | nM | 7.22 |
| CHEMBL62717 | — | Ki | = | 600.0 | nM | 6.22 |
| CHEMBL178982 | — | Ki | = | 600.0 | nM | 6.22 |
| CHEMBL82941 | — | Ki | = | 800.0 | nM | 6.10 |
| CHEMBL189314 | — | Ki | = | 1000.0 | nM | 6.00 |
| CHEMBL24547 | — | Ki | = | 2200.0 | nM | 5.66 |
| CHEMBL278785 | — | Ki | = | 2200.0 | nM | 5.66 |