Assay Detail
Binding
CHEMBL838624
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Binding affinity for 5-hydroxytryptamine 4 receptor in rat was determined by rat tunica muscularis mucosae assay
3
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Muscularis mucosa |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Azaadamantane benzamide 5-HT4 agonists: gastrointestinal prokinetic SC-54750.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.27 | 7.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3085015 | — | — | 1 | 7.29 |
| CHEMBL295155 | — | — | 2 | 7.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3085015 | — | Ki | = | 51.0 | nM | 7.29 |
| CHEMBL295155 | — | Ki | = | 57.0 | nM | 7.24 |
| CHEMBL295155 | — | Ki | > | 500.0 | nM | - |