Assay Detail
Binding
CHEMBL838682
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Binding affinity against alpha-Mannosidase isolated from Jack bean
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Canavalia ensiformis |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Functionalized pyrrolidines inhibit alpha-mannosidase activity and growth of human glioblastoma and melanoma cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.17 | 7.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL190311 | — | — | 1 | 7.72 |
| CHEMBL191531 | — | — | 1 | 4.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL190311 | — | Ki | = | 19.0 | nM | 7.72 |
| CHEMBL191531 | — | Ki | = | 24000.0 | nM | 4.62 |