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Assay Detail

CHEMBL838702

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Binding
Binding affinity for human melanocortin 3 receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Expert

Target

Melanocortin receptor 3 (CHEMBL4644)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Identification of agonists and antagonists of the human melanocortin-4 receptor from piperazinebenzylamines.
Tran JA, Pontillo J, Arellano M, White NS, Fleck BA, Marinkovic D, Tucci FC, Lanier M, Nelson J, Saunders J, Foster AC, Chen C.
Bioorg Med Chem Lett (2005) 15 : 833 -837
PubMed 15664867 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 5.96 6.20

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL183799 1 6.20
CHEMBL182277 1 5.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL183799 Ki = 630.0 nM 6.20
CHEMBL182277 Ki = 1900.0 nM 5.72