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Assay Detail

CHEMBL838830

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Binding
Binding constant for Opioid receptor mu 1 in mouse
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Confidence 9 — Direct single protein target
Curated By Expert

Target

Mu-type opioid receptor (CHEMBL2858)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

18F-labeled sufentanil for PET-imaging of mu-opioid receptors.
Henriksen G, Platzer S, Hauser A, Willoch F, Berthele A, Schwaiger M, Wester HJ.
Bioorg Med Chem Lett (2005) 15 : 1773 -1777
PubMed 15780604 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 3 9.77 10.62

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2311157 [11C]-CARFENTANIL 1.0 1 10.62
CHEMBL196960 1 10.00
CHEMBL197479 1 8.68

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2311157 [11C]-CARFENTANIL Ki = 0.024 nM 10.62
CHEMBL196960 Ki = 0.1 nM 10.00
CHEMBL197479 Ki = 2.1 nM 8.68