Assay Detail
Binding
CHEMBL838832
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity against bovine Tachykinin receptor 2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Design and synthesis of substituted N-methylbenzamide analogues derived from SR 48,968 as neurokinin-2 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.15 | 9.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL308148 | SAREDUTANT | 3.0 | 1 | 9.30 |
| CHEMBL71397 | — | — | 1 | 9.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL308148 | SAREDUTANT | Ki | = | 0.5 | nM | 9.30 |
| CHEMBL71397 | — | Ki | = | 1.0 | nM | 9.00 |