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Assay Detail

CHEMBL839445

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity towards alpha-Mannosidase isolated from Almond
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Prunus dulcis
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Alpha-mannosidase (CHEMBL4193)
Type SINGLE PROTEIN
Organism Glycine max

Publication

Functionalized pyrrolidines inhibit alpha-mannosidase activity and growth of human glioblastoma and melanoma cells.
Fiaux H, Popowycz F, Favre S, Schütz C, Vogel P, Gerber-Lemaire S, Juillerat-Jeanneret L.
J Med Chem (2005) 48 : 4237 -4246
PubMed 15974577 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 5.02 5.02

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL425723 1 5.02
CHEMBL425364 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL425723 Ki = 9500.0 nM 5.02
CHEMBL425364 Ki = 600000.0 nM -