Assay Detail
Binding
CHEMBL842477
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Compound was evaluated for its binding affinity against enkephalin mu receptor using [3H]PL-017 as ligand in rat cerebrum in vitro
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Cerebrum |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
New potent enkephalin analogs containing trifluoromethylamino acid residues
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 9.00 | 9.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL302523 | — | — | 1 | 9.30 |
| CHEMBL13786 | — | — | 1 | 8.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL302523 | — | IC50 | = | 0.5 | nM | 9.30 |
| CHEMBL13786 | — | IC50 | = | 2.0 | nM | 8.70 |