Assay Detail
Binding
CHEMBL843419
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Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptors.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Corticotropin-releasing factor receptor 1 (CHEMBL1800) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Corticotropin releasing factor (CRF) receptor modulators: progress and opportunities for new therapeutic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.58 | 8.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL297868 | — | — | 1 | 8.89 |
| CHEMBL295563 | — | — | 1 | 8.55 |
| CHEMBL290762 | — | — | 1 | 8.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL297868 | — | Ki | = | 1.3 | nM | 8.89 |
| CHEMBL295563 | — | Ki | = | 2.8 | nM | 8.55 |
| CHEMBL290762 | — | Ki | = | 5.0 | nM | 8.30 |