Assay Detail
Binding
CHEMBL843465
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Inhibitory concentration against mu-opioid receptor in guinea pig ileum
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Possible contribution of a glutathione conjugate to the long-duration action of beta-funaltrexamine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.79 | 8.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL473136 | — | — | 1 | 8.32 |
| CHEMBL610547 | — | — | 1 | 7.66 |
| CHEMBL610549 | — | — | 1 | 7.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL473136 | — | IC50 | = | 4.8 | nM | 8.32 |
| CHEMBL610547 | — | IC50 | = | 22.0 | nM | 7.66 |
| CHEMBL610549 | — | IC50 | = | 41.0 | nM | 7.39 |