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Assay Detail

CHEMBL844178

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Functional
Compound was tested in vitro for inhibition of tubulin polymerization
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Tubulin alpha chain (CHEMBL3658)
Type SINGLE PROTEIN
Organism Sus scrofa

Publication

Synthesis and antiproliferative activity of a cyclic analog of dolastatin 10.
Poncet J, Hortala L, Busquet M, Guéritte-Voegelein F, Thoret S, Pierré A, Atassi G, Jouin P.
Bioorg Med Chem Lett (1998) 8 : 2855 -2858
PubMed 9873636 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.41 4.41

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL318667 1 4.41

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL318667 IC50 = 39000.0 nM 4.41