Assay Detail
Binding
CHEMBL845232
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of [3H]U-69593 binding to kappa opioid receptor of guinea pig brain homogenate
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Brain |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Design and synthesis of highly potent and selective cyclic dynorphin A analogs. 2. New analogs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.38 | 9.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL415406 | — | — | 1 | 9.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL415406 | — | IC50 | = | 0.42 | nM | 9.38 |