Assay Detail
Binding
CHEMBL847428
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Compound was tested in vitro for inhibition of tissue plasminogen activator
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
(N-acyl-N-alkyl)glycyl borolysine analogs: A new class of potent thrombin inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 9 | 6.26 | 8.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL290376 | — | — | 1 | 8.24 |
| CHEMBL95940 | — | — | 1 | 7.29 |
| CHEMBL101759 | — | — | 1 | 6.55 |
| CHEMBL99309 | — | — | 1 | 6.17 |
| CHEMBL317137 | — | — | 1 | 6.12 |
| CHEMBL419892 | — | — | 1 | 5.96 |
| CHEMBL330206 | — | — | 1 | 5.47 |
| CHEMBL317682 | — | — | 1 | 5.42 |
| CHEMBL95993 | — | — | 1 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL290376 | — | Ki | = | 5.7 | nM | 8.24 |
| CHEMBL95940 | — | Ki | = | 51.0 | nM | 7.29 |
| CHEMBL101759 | — | Ki | = | 280.0 | nM | 6.55 |
| CHEMBL99309 | — | Ki | = | 680.0 | nM | 6.17 |
| CHEMBL317137 | — | Ki | = | 750.0 | nM | 6.12 |
| CHEMBL419892 | — | Ki | = | 1100.0 | nM | 5.96 |
| CHEMBL330206 | — | Ki | = | 3370.0 | nM | 5.47 |
| CHEMBL317682 | — | Ki | = | 3800.0 | nM | 5.42 |
| CHEMBL95993 | — | Ki | = | 7000.0 | nM | 5.16 |