Assay Detail
Binding
CHEMBL847453
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In vitro inhibitory activity against rat testosterone 5 alpha reductase was determined
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Synthesis and 5 alpha-reductase inhibitory activities of benzofuran derivatives with a carbamoyl group.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 7.18 | 7.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL359360 | — | — | 1 | 7.58 |
| CHEMBL152401 | — | — | 1 | 7.54 |
| CHEMBL155094 | — | — | 1 | 7.45 |
| CHEMBL153258 | — | — | 1 | 7.42 |
| CHEMBL25083 | — | — | 1 | 6.93 |
| CHEMBL155568 | — | — | 1 | 6.81 |
| CHEMBL422865 | — | — | 1 | 6.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL359360 | — | IC50 | = | 26.3 | nM | 7.58 |
| CHEMBL152401 | — | IC50 | = | 28.5 | nM | 7.54 |
| CHEMBL155094 | — | IC50 | = | 35.5 | nM | 7.45 |
| CHEMBL153258 | — | IC50 | = | 37.9 | nM | 7.42 |
| CHEMBL25083 | — | IC50 | = | 118.0 | nM | 6.93 |
| CHEMBL155568 | — | IC50 | = | 155.0 | nM | 6.81 |
| CHEMBL422865 | — | IC50 | = | 279.0 | nM | 6.55 |