Assay Detail
Binding
CHEMBL847601
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration against thrombin.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
PRO_SELECT: combining structure-based drug design and array-based chemistry for rapid lead discovery. 2. The development of a series of highly potent and selective factor Xa inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 5.45 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL20672 | — | — | 1 | 5.80 |
| CHEMBL20733 | — | — | 1 | 5.10 |
| CHEMBL19902 | DX-9065A | — | 1 | - |
| CHEMBL20240 | YM-60828 | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL20672 | — | Ki | = | 1600.0 | nM | 5.80 |
| CHEMBL20733 | — | Ki | = | 8000.0 | nM | 5.10 |
| CHEMBL19902 | DX-9065A | Ki | > | 2000.0 | nM | - |
| CHEMBL20240 | YM-60828 | Ki | > | 10000.0 | nM | - |