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Assay Detail

CHEMBL848476

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was evaluated for the Inositol phosphate accumulation in rat skin fibroblasts.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Confidence 1 — Organism
Curated By Intermediate

Target

Rattus norvegicus (CHEMBL376)
Type ORGANISM
Organism Rattus norvegicus

Publication

Endothelin: a new challenge.
Doherty AM.
J Med Chem (1992) 35 : 1493 -1508
PubMed 1315867 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 5.85 5.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL289687 1 5.85
CHEMBL38071 1 -
CHEMBL34540 1 -
CHEMBL432091 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL289687 IC50 = 1400.0 nM 5.85
CHEMBL38071 IC50 < 50000.0 nM -
CHEMBL34540 IC50 < 50000.0 nM -
CHEMBL432091 IC50 < 50000.0 nM -