Assay Detail
Functional
CHEMBL853176
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effect on human PPARgamma transactivation in 293T cells
27
Total Activities
27
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | 293T |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Peroxisome proliferator-activated receptor gamma (CHEMBL235) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
1,3,5-Trisubstituted aryls as highly selective PPARdelta agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 27 | 6.16 | 6.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL207569 | — | — | 1 | 6.43 |
| CHEMBL207570 | — | — | 1 | 6.13 |
| CHEMBL379123 | — | — | 1 | 5.92 |
| CHEMBL208755 | — | — | 1 | - |
| CHEMBL381066 | — | — | 1 | - |
| CHEMBL207957 | — | — | 1 | - |
| CHEMBL383313 | — | — | 1 | - |
| CHEMBL207811 | — | — | 1 | - |
| CHEMBL207318 | — | — | 1 | - |
| CHEMBL377093 | — | — | 1 | - |
| CHEMBL208203 | — | — | 1 | - |
| CHEMBL206578 | — | — | 1 | - |
| CHEMBL208202 | — | — | 1 | - |
| CHEMBL425945 | — | — | 1 | - |
| CHEMBL383404 | — | — | 1 | - |
| CHEMBL207887 | — | — | 1 | - |
| CHEMBL208318 | — | — | 1 | - |
| CHEMBL377695 | — | — | 1 | - |
| CHEMBL210873 | — | — | 1 | - |
| CHEMBL211047 | — | — | 1 | - |
| CHEMBL379145 | — | — | 1 | - |
| CHEMBL206895 | — | — | 1 | - |
| CHEMBL207449 | — | — | 1 | - |
| CHEMBL379851 | — | — | 1 | - |
| CHEMBL210469 | — | — | 1 | - |
| CHEMBL207198 | — | — | 1 | - |
| CHEMBL377883 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL207569 | — | EC50 | = | 370.0 | nM | 6.43 |
| CHEMBL207570 | — | EC50 | = | 740.0 | nM | 6.13 |
| CHEMBL379123 | — | EC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL208755 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL381066 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL207957 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL383313 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL207811 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL207318 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL377093 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL208203 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL206578 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL208202 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL425945 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL383404 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL207887 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL208318 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL377695 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL210873 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL211047 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL379145 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL206895 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL207449 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL379851 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL210469 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL207198 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL377883 | — | EC50 | > | 10000.0 | nM | - |