Compound Detail
CHEMBL207570
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Basic Information
| ChEMBL ID | CHEMBL207570 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UDWOWKJZJXETKQ-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
424.5
MW (Da)
6.37
ALogP
3
HBA
1
HBD
55.8
PSA (Ų)
0.36
QED
1
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 6.25
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor delta CHEMBL3979 | EC50 | 6.25 | 6.25 | 560.0 | 1 |
| Peroxisome proliferator-activated receptor gamma CHEMBL235 | EC50 | 6.13 | 6.13 | 740.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor delta | EC50 | = | 560.0 | nM | 6.25 | Effect on human PPARdelta transactivation in 293T cells | 16546385 |
| Peroxisome proliferator-activated receptor gamma | EC50 | = | 740.0 | nM | 6.13 | Effect on human PPARgamma transactivation in 293T cells | 16546385 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16546385 | 10.1016/j.bmcl.2006.02.079 | Peroxisome proliferator-activated receptor gamma | 2 |
| 16546385 | 10.1016/j.bmcl.2006.02.079 | Peroxisome proliferator-activated receptor delta | 2 |
| 16546385 | 10.1016/j.bmcl.2006.02.079 | Peroxisome proliferator-activated receptor alpha | 1 |
Data from ChEMBL 36 via Core Engine