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Assay Detail

CHEMBL853208

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against HIV1 in human PBM cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human immunodeficiency virus 1
Cell Type PBM
Confidence 1 — Organism
Curated By Expert

Target

Human immunodeficiency virus 1 (CHEMBL378)
Type ORGANISM
Organism Human immunodeficiency virus 1

Publication

Facile purification of honokiol and its antiviral and cytotoxic properties.
Amblard F, Delinsky D, Arbiser JL, Schinazi RF.
J Med Chem (2006) 49 : 3426 -3427
PubMed 16722664 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 4.82 5.48

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL16901 HONOKIOL 1 5.48
CHEMBL180920 MAGNOLOL 1 4.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL16901 HONOKIOL EC50 = 3300.0 nM 5.48
CHEMBL180920 MAGNOLOL EC50 = 69300.0 nM 4.16