Assay Detail
Binding
CHEMBL853294
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Antagonizing activity of CCK8 induced amylase secretion from rat pancreatic acini
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Conformationally constrained CCK4 analogues incorporating IBTM and BTD beta-turn mimetics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.49 | 6.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL382953 | — | — | 1 | 6.89 |
| CHEMBL198902 | — | — | 1 | 6.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL382953 | — | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL198902 | — | IC50 | = | 829.0 | nM | 6.08 |